C2gap2 is a common regulator of ras signaling for chemotaxis, phagocytosis, and macropinocytosis

HIGHLIGHTS

  • who: Xuehua Xu and collaborators from the UCONN Health, United States University of Nevada, Reno have published the article: C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis, in the Journal: (JOURNAL)
  • what: The authors identified C2GAP2, a highly expressed RasGAP protein in vegetative stage, that regulates folic acid-mediated chemotaxis, phagocytosis, and macropinocytosis in D. discoideum.
  • how: The authors investigated the requirement of the C2 domain for C2GAP2`s interaction with Ras by immunoprecipitation analysis . Images were further processed in Adobe Photoshop (Adobe Systems San Jose CA) and . . .

     

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