C698r mutation in lrsam1 gene impairs nerve regeneration in a cmt2p mouse model

HIGHLIGHTS

  • who: Daniel Moiseev from the DepartmentState University have published the research work: C698R mutation in Lrsam1 gene impairs nerve regeneration in a CMT2P mouse model, in the Journal: Scientific Reports Scientific Reports
  • what: The authors have shown the production and initial characterization toward a new mouse model of CMT2P, where a knock-in of the C698R Lrsam1 mutation was introduced into the mouse genome.
  • how: The model was implemented in ORS Dragonfly software trained with ~ 150 mouse sciatic nerve images and their respective myelin segmentations. For the experiments the authors used cells out . . .

     

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