C9orf72 hexanucleotide repeat expansion-related neuropathology is attenuated by nasal rifampicin in mice

HIGHLIGHTS

  • who: Yukari Hatanaka and collaborators from the Department of Translational Neuroscience, Osaka City University Graduate School of Medicine, Life Science Research Institute, Kindai University, Osakasayama, Japan have published the article: C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice, in the Journal: Biomedicines 2022, 10, 1080. of 27/03/2022
  • what: The authors studied the effects of rifampicin on the formation of RNA foci and cytoplasmic inclusions composed of DPRs or TDP-43 in the brains of C9-500 mice.
  • how: Previously the authors showed that a well-known . . .

     

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