Ca2+-activated k+ channels and the regulation of the uteroplacental circulation

HIGHLIGHTS

  • who: Xiang-Qun Hu and Lubo Zhang from the Loma Linda University, Loma Linda, CA, USA have published the article: Ca2+-Activated K+ Channels and the Regulation of the Uteroplacental Circulation, in the Journal: (JOURNAL)
  • what: Uteroplacental blood flow increases markedly in pregnancy to meet the demand for placental and fetal growth.

SUMMARY

    Vasoconstriction is initiated by an increasei primarily due to Ca2+ influx mediated by the L-type voltage-dependent Ca2+ (CaV 1.2) channel in the plasma_membrane and/or Ca2+ release mediated by ryanodine (RyR)/inositol trisphosphate (IP3 R . . .

     

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