Ca2+ binding to synapsin i regulates resting ca2+ and recovery from synaptic depression in nerve terminals

HIGHLIGHTS

  • who: Matteo Moschetta from the Center for Neuroscience and Technology, Genoa, Italy Department of Experimental Medicine, University have published the research work: Ca2+ binding to synapsin I regulates resting Ca2+ and recovery from synaptic depression in nerve terminals, in the Journal: (JOURNAL) of September/22,/2010
  • what: The authors show that ATP and u00adC a 2+ binding by the SynI C-domain are independent events that, however, cooperatively potentiate each other.

SUMMARY

    All Syn isoforms display a highly conserved ATP binding_site in the central C-domain. A 200 ns-long simulation . . .

     

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