Ca2+ permeable ampa channels in diseases of the nervous system

HIGHLIGHTS

  • who: John H. Weiss from the Department of Neurology, University of California Irvine, Irvine, CA, USA have published the research: Ca2+ permeable AMPA channels in diseases of the nervous system, in the Journal: (JOURNAL)

SUMMARY

    Whereas most adult neurons possess relatively few of these channels, discrete populations of neurons, most prominently many GABAergic inhibitory interneurons, possess large numbers of Ca-AMPA channels (Jonas et_al, 1994; Yin et_al, 1994a; Leranth et_al, 1996). Providing strong evidence that Ca-AMPA channels play a role in this form of the disease, generation of SOD1 mutant mice with . . .

     

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