Caenorhabditis elegans paqr-2 and iglr-2 protect against glucose toxicity by modulating membrane lipid composition

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  • who: Emma Svensk and colleagues from the Department of Chemistry and Molecular Biology, University of have published the article: Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition, in the Journal: (JOURNAL) of March/16,/2016
  • what: The authors show that C. mutants lacking paqr-2 the worm homolog of the adiponectin receptors AdipoR1/2 or its newly identified functional partner are glucose intolerant and die in the presence of as little as 20 mM glucose. Using bimolecular fluorescence complementation the authors also show that PAQR-2 and . . .

     

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