Caf08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns

HIGHLIGHTS

• who: Simon D. Haren from the s Hospital, Boston, MA, USAUniversity of have published the research work: CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate that synergistic TLR7/8 and Mincle stimulation activates antigen cross-presenting pathways in_vitro and protects against RSV infection in newborn mice, correlating with Th1-skewed CD4+ and CD8+ T_cell responses towards the RSV pre-F antigen in_vivo. Because the primary objective of the study was to evaluate the ability of the formulation to . . .
  

   

  

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