Calcium handling maturation and adaptation to increased substrate stiffness in human ipsc-derived cardiomyocytes: the impact of full-length dystrophin de ciency

HIGHLIGHTS

  • who: . et al. from the University of Aberdeen, United Kingdom have published the research: Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin de ciency, in the Journal: (JOURNAL)
  • what: The first issue that this work seeks to address are the possible effects of cardiomyopathyassociated mutations on the cardiac differentiation and Recent evidence suggested that abnormalities of cardiomyocyte maturation and cardiac muscle development contribute to functional and structural cardiac anomalies in genetically-determined cardiomyopathies (Girolami et_al, 2022). The final aim of the study is . . .

     

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