Calcium influx factor directly activates store-operated cation channels in vascular smooth muscle cells*

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  • who: Elena S. Trepakova from the (UNIVERSITY) have published the Article: Calcium Influx Factor Directly Activates Store-operated Cation Channels in Vascular Smooth Muscle Cells*, in the Journal: (JOURNAL) of May/30,/2000
  • what: The authors report that these 3-pS channels are activated in inside-out membrane patches from SMC immediately upon application of Ca2ⴙ influx factor (CIF) extracted from mutant yeast, which has been previously shown to activate Ca2ⴙ influx in Xenopus oocytes and Ca2ⴙ release-activated Ca2ⴙ current in Jurkat cells. The amplitude of single channel currents was analyzed using all-point . . .

     

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