HIGHLIGHTS
- who: Paleerath Peerapen from the of Medicine Siriraj Hospital, Mahidol University, th Floor u2011 SiMR Building, Wanglang Road, Bangkoknoi, Bangkok, Thailand have published the research work: Calcium oxalate crystals trigger epithelial-mesenchymal transition and carcinogenic features in renal cells: a crossroad between kidney stone disease and renal cancer, in the Journal: (JOURNAL)
SUMMARY
Several reports have shown intratumoral deposition of calcium_oxalate (CaOx) crystals in RCC. COM crystals cause renal cell injury, induce reactive oxygen species (ROS) overproduction, and promote oxidative modifications of cellular proteins. A previous study has revealed positive staining of oxidative . . .
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