Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site

HIGHLIGHTS

• who: Stephan Kellenberger et al. from the Department of biomedical Sciences, University of Lausanne, Lausanne, Switzerland have published the Article: Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site, in the Journal: (JOURNAL) of 21/Dec/2022
• what: The authors show that in addition to the previously The authors show here that at high Ca2+ concentrations, the pH dependence of activation and of SSD is shifted to more acidic values.

SUMMARY

MD simulations predict candidate Ca2+ binding_sites To . . .

 



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