Calmodulin fishing with a structurally disordered bait triggers cyaa catalysis

HIGHLIGHTS

• who: Darragh P. O#_#x2019 and collaborators from the CITECH, Paris, France have published the Article: Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis, in the Journal: (JOURNAL) of October/10,/2017
• what: Using a combination of small-angle X-ray scattering (SAXS) hydrogen/deuterium exchange mass spectrometry (HDX-MS) and synchrotron radiation circular dichroism (SRCD) the authors show that in the absence of CaM AC exhibits significant structural disorder and a 75-residue-long stretch within AC undergoes a disorder-to-order transition upon CaM binding. The authors propose that the . . .
  

   

  

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