HIGHLIGHTS
- who: Monoclonal antibodies targeting nonstructural and colleagues from the DivisionCardiff University for Virus Research, Glasgow, United Kingdom have published the research: can activate ADCC against human cytomegalovirus, in the Journal: (JOURNAL)
- how: Surprisingly the antigens that the authors identified as mediating ADCC were not the classical viral structural proteins that ADCC studies have traditionally focused on.
- future: Future work will be required to demonstrate both safety and efficacy in humans.
SUMMARY
Human cytomegalovirus (HCMV) establishes lifelong infection in the face of robust humoral and cell-mediated immune_responses. In contrast . . .
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