Canagliflozin, characterized as a hdac6 inhibitor, inhibits gastric cancer metastasis

HIGHLIGHTS

  • who: Dandan Jiang from the Oncotelic, Inc, United States Taipei Medical University, Taiwan have published the paper: Canagliflozin, characterized as a HDAC6 inhibitor, inhibits gastric cancer metastasis, in the Journal: (JOURNAL)
  • what: The authors took advantage of FDAapproved drug library and indicated that canagliflozin effectively inhibits the enzymatic activity of HDAC6 and shows an excellent affinity with HDAC6.
  • how: Data were analyzed using GraphPad Prism 8.0 (USA). t-test or one-way analysis of variance (ANOVA) was used for the statistical significance evaluation. As gastric cancer is one of the leading causes . . .

     

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