Canagliflozin promotes osteoblastic mc3t3-e1 differentiation via ampk/runx2 and improves bone microarchitecture in type 2 diabetic mice

HIGHLIGHTS

  • who: Peiyang Song and collaborators from the Hospital, Taiwan Medical University have published the article: Canagliflozin promotes osteoblastic MC3T3-E1 differentiation via AMPK/RUNX2 and improves bone microarchitecture in type 2 diabetic mice, in the Journal: (JOURNAL)
  • what: Although the study had significant discoveries in bone differentiation, the functions of canagliflozin in bone Frontiers in Endocrinology
  • how: Data were analyzed using one-way ANOVA for three independent experiments. of RUNX2 after treatment with the inhibitor and the activator of AMPK. The authors developed a model to illustrate AMPK-mediated osteoblastic differentiation under HG . . .

     

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