HIGHLIGHTS
- who: Charalampos Fotsitzoudis and colleagues from the Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece have published the article: Cancer-Associated Fibroblasts: The Origin, Biological Characteristics and Role in Canceru2014A Glance onColorectal Cancer, in the Journal: Cancers 2022, 4394 of /2022/
SUMMARY
TME consists of the extracellular matrix (ECM) and different cells and micromolecules (tumor cells, immune cells, vasculature and cancer-associated fibroblasts (CAFs)). CAFs are fibroblasts with a crucial role in tumor growth and metastasis by interacting with cancer cells via various mechanisms, such as exosomes, production of . . .
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