HIGHLIGHTS
- who: Andreas Ritter from the (UNIVERSITY) have published the paper: Cancer-educated mammary adipose tissue-derived stromal/stem cells in obesity and breast cancer: spatial regulation and function, in the Journal: (JOURNAL)
- what: The authors show that ln-aT bASCs are susceptible to be transformed into an inflammatory cancer-associated phenotype whereas ob-aT bASCs are prone to be cancer-educated into a myofibroblastic phenotype. Significance This study provides mechanistic insights into how obesity affects the phenotype of bASCs in the TME. The authors show that these breast cancer associated bASCs highly reduce their differentiation . . .
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