Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells

HIGHLIGHTS

  • who: Kouichi Tabu from the Department of Stem Cell Regulation, Medical Research Institute, Tokyo Medical Dental University (TMDU), Tokyo, u20118510, Japan have published the paper: Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells, in the Journal: (JOURNAL)
  • what: This study provides a broad significance not only in demonstrating a tumor beneficial role of necrosis for CSC-driven niche construction but also in proposing the presence of M1 markerexpressing Mu03c6s with protumoral functions.
  • future: Investigations are needed to unravel whether GSC-derived soluble factor(s . . .

     

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