HIGHLIGHTS
- who: Top from the Department of Surgery, Oncology, and Gastroenterology, Oncology Section, University of Padova, Padova, Italy have published the Article: Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose, in the Journal: (JOURNAL)
- what: The authors show that an ex vivo isolated population of EOC cells co-expressing CD44 and CD117, the two critical markers of CSC, shows a metabolic profile characterized by high glucose uptake and preferential fuelling of glucose into oxidative_phosphorylation (OXPHOS) and the pentose_phosphate_pathway.
- how: Similar results were obtained with metformin which also inhibits . . .
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