Cancer susceptibility as a cost of reproduction and contributor to life history evolution

HIGHLIGHTS

SUMMARY

    The short- and long-term fitness consequences of oncogenic manifestations early in life, at a life-history stage where individuals are expected to maximize their allocation of resources toward growth and reproduction, remain poorly documented (Vittecoq et_al, 2013; Thomas et_al, 2018). For instance, malignancies affecting reproductive organs, like cervix, uterus, endometrial, ovary or testicular cancers, can severely compromise their host`s reproductive potential by triggering reproductive aging or inducing infertility (Brinton et_al, 2004, 2005; Paduch, 2006; Singh et_al, 2011; Hanson et_al, 2017). For instance, reproductive activities and allocation to immune function are often mutually . . .

     

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