Canine osteosarcoma in comparative oncology: molecular mechanisms through to treatment discovery

HIGHLIGHTS

  • who: Siobhan Simpson from the University of Turin, Italy have published the research: Canine osteosarcoma in comparative oncology: Molecular mechanisms through to treatment discovery, in the Journal: (JOURNAL)
  • what: This research showed that expression miR223 increases and in let-7b and miR-130a decreases were associated with increased risk and a shorter disease free interval. This study showed only mild side-effects of ADXS31-164 when administered to canine patients.
  • future: Despite differences compared to some cancers this outcome agreed with DKK3 knockdown in cells overexpressing NKD2 which exhibited increased proliferation indicating a . . .

     

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