Canonical pi3kγ signaling in myeloid cells restricts trypanosoma cruzi infection and dampens chagasic myocarditis

HIGHLIGHTS

• who: Maria C. Silva from the Medical School University of Sao Paulo, Bandeirantes , Ribeiru00e3o Preto, SP, Brazil have published the article: Canonical PI3Ku03b3 signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 12/09/2016
• what: The authors show that the canonical PI3Ku03b3 is involved in the pathophysiology of chagasic heart disease. The authors investigated the role of PI3Ku03b3 signaling in the heart of T. cruzi-infected mice and humans. Consistently, the authors propose that PI3Ku03b3 signaling might be a protective mechanism that restricts . . .
  

   

  

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