HIGHLIGHTS
- who: Takahiro Sogo from the (UNIVERSITY) have published the Article: Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells, in the Journal: (JOURNAL)
- what: In the present study, we, for the first time, developed GPCR-based CARs, which are able to activate endogenous Wnt3a signaling in mouse ES cells. The study has the potential to boost in_vivo application of Wnt3a-diCAR in tissue regeneration. In this study, Wnt3a-diCARs were introduced into ES cells via lentiviral_vectors, which is a highly efficient way to test cellular functions of . . .
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