Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth*

HIGHLIGHTS

• who: George D. Kamphaus from the (UNIVERSITY) have published the Article: Canstatin, a Novel Matrix-derived Inhibitor of Angiogenesis and Tumor Growth*, in the Journal: (JOURNAL) of August/18,/1999
• what: The authors demonstrate that apoptosis induced by canstatin was associated with a down-regulation of the anti-apoptotic protein, FLIP. The laboratory evaluated the anti-angiogenic potential of all six NC1 domains of type IV collagen, and in the present study, the authors demonstrate the ability of the NC1 domain of the ␣2 chain of type IV collagen, which the authors have named canstatin . . .
  

   

  

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