Capsid and genome modification strategies to reduce the immunogenicity of adenoviral vectors

HIGHLIGHTS

  • who: Florian Kreppel and Claudia Hagedorn from the Center for Biomedical Education and Research (ZBAF), Witten/Herdecke University (UW/H), Stockumer Str10, Witten, Germany have published the article: Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral Vectors, in the Journal: (JOURNAL)
  • what: Adenovirus vectors belong to the most immunogenic vectors.
  • future: By combining both approaches with constant results from the discovery of additional rare Ad types and Ad species it appears very likely that improved gene transfer vectors Ad-based genetic vaccines and oncolytics will be developed in the near . . .

     

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