Caqk, a peptide associating with extracellular matrix components targets sites of demyelinating injuries

HIGHLIGHTS

  • who: Barbara Ranscht from the Northwestern University, United have published the article: CAQK, a peptide associating with extracellular matrix components targets sites of demyelinating injuries, in the Journal: (JOURNAL)
  • what: The authors report selective targeting of CAQK to injured but not intact myelin in the three demyelination models and thus open prospects for exploring the potential utility of CAQK towards myelin repair. The authors report that the four amino_acid peptide CAQK selectively targets demyelinating lesions. The authors show that upon systemic administration and 1 h in circulation, CAQK homes specifically to sites of CNS demyelinating . . .

     

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