Carbon monoxide-induced tfeb nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury

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  • who: Hyo Jeong Kim from the All experiments with mice were approved by the Animal Care Committee of the University of UlsanC BL/, mice (, weeks old, male) were purchased from ORIENT (Busan, Korea). For the fulminant hepatitis mouse model, mice (, weeks old, male) were injected with LPS (0., μg/mouse, inraperitoneally (i.p.)) and, GalN hydrochloride (, mg/mouse, i.p.). Mice (N=5) were subjected to inhalation of air or CO at , parts per million (p.p.m.) in air (Core Gas Ulsan, Korea) for , days (, h/day) before challenge with LPS and, GalN in a sealed . . .

     

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