Carbonic anhydrase ix is a ph-stat that sets an acidic tumour extracellular ph in vivo

HIGHLIGHTS

  • who: Shen-Han Lee from the University of o de Investigaciones BiomĂ©dicas "Alberto Sols", c/ Arturo Duperier, Madrid, Spain have published the research work: Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo, in the Journal: (JOURNAL) of 26/06/2018
  • what: The authors propose, therefore, that whereas other membrane H+ transport mechanisms such as the Na+/H+-exchanger and the vacuolar ATP-dependent H+ pump are primarily concerned with maintaining a constant pHi, extracellular CA catalysis endows CAIX-expressing cancer cells with the ability to set . . .

     

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