Carboplatin restricts peste des petits ruminants virus replication by suppressing the sting-mediated autophagy

HIGHLIGHTS

  • What: The authors analyzed the influence of Carboplatin in morbilliviruses infection and found for the first time that Carboplatin inhibits PPRV replication in Vero cells.
  • Who: Rui Zhang et al. from the University of Naples Federico II, Italy have published the research work: Carboplatin restricts peste des petits ruminants virus replication by suppressing the STING-mediated autophagy, in the Journal: (JOURNAL)
  • How: Transmission electron microscopy assay results showed that the morphological swelling and dilation of ER in Carboplatintreated PPRV-infected Vero cells was more severe than that observed in untreated PPRV-infected cells . . .

     

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