Carboxyl-terminal proteolytic processing of cux1 by a caspase enables transcriptional activation in proliferating cells*

HIGHLIGHTS

  • who: Mary Truscott from the (UNIVERSITY) have published the Article: Carboxyl-terminal Proteolytic Processing of CUX1 by a Caspase Enables Transcriptional Activation in Proliferating Cells*, in the Journal: (JOURNAL) of October/12,/2007
  • what: The authors demonstrated a proteolytic processing event that results in the removal of the carboxyl-terminal region of the CUX1 transcription factor.
  • how: The following day cells were fixed and stained with propidium iodide and the DNA content was analyzed.

SUMMARY

    Caspase-3, -6, and -7, the effector caspases, are present as inactive dimers that . . .

     

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