HIGHLIGHTS
- who: Shreya Raghavan and colleagues from the Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, USA have published the paper: Carcinoma-Associated Mesenchymal Stem Cells Promote Chemoresistance in Ovarian Cancer Stem Cells via PDGF Signaling, in the Journal: Cancers 2020, x of /2020/
- what: Using this model, the authors aimed to investigate the hypothesized PDGF-BB/PDGFR-β signaling and its downstream effects on functional CSC behaviors, including migratory potential, tumorigenicity and platinum resistance. The work demonstrates the specific involvement of the growth factor PDGF-BB in this platinum resistance phenomenon, in . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.