HIGHLIGHTS
- who: Camille Danne u200d u200d et al. from the (UNIVERSITY) have published the paper: CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival, in the Journal: (JOURNAL) of 17/06/2020
- what: The authors show that CARD9 expression in neutrophils, but not in epithelial or CD11c+cells such as dendritic cells, protects against dextran sulfate sodium (DSS)-u00ad induced colitis in mice. The authors show that CARD9 mediates mitochondrial function and apoptosis in neutrophils, especially in an oxidative environment. Other cell types are likely involved in the Card9-/- mice phenotype, explaining . . .
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