Card9 is a novel caspase recruitment domain-containing protein that interacts with bcl10/clap and activates nf-κb*

HIGHLIGHTS

• who: John Bertin from the (UNIVERSITY) have published the Article: CARD9 Is a Novel Caspase Recruitment Domain-containing Protein That Interacts With BCL10/CLAP and Activates NF-κB*, in the Journal: (JOURNAL) of October/12,/2000
• what: The authors propose here that CARD9 is an upstream activator of BCL10 and NF-␬B signaling. are protein modules found extensively in proteins that mediate apoptotic signaling .

SUMMARY

The N-terminal caspase recruitment domain (CARD) of BCL10 has been proposed to function as an activation domain that mediates homophilic interactions with an upstream CARD . . .

 



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