Cardiac pericyte reprogramming by mek inhibition the ischemic heart bristol medical

HIGHLIGHTS

  • who: Elisa Avolio and collaborators from the Bristol Heart Institute University of Edinburgh, Edinburgh, United Kingdom have published the article: Cardiac pericyte reprogramming by MEK inhibition the ischemic heart Bristol Medical, in the Journal: (JOURNAL)
  • what: This study aimed to determine whether induced phenotypic transition of myocardial PCs can aid heart neovascularization. The authors believe that this study provides a new mechanistic understanding of cardiac PC potential in vascular remodeling. The authors show that myocardial vascularization can be pharmacologically modulated in_vivo using the selective MEKi PD0325901, although differences were observed between the normoperfused and the . . .

     

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