Cardiac xenotransplantation: progress in preclinical models and prospects for clinical translation

HIGHLIGHTS

  • who: Avneesh K. Singh and collaborators from the Department of Surgery, School of Medicine, University of Maryland, Baltimore, MD, United States, Revivicor Inc, Blacksburg have published the article: Cardiac Xenotransplantation: Progress in Preclinical Models and Prospects for Clinical Translation, in the Journal: (JOURNAL)

SUMMARY

    Xenotransplantation (XTx) is an alternative source of a human organ for patients with end-stage organ failure. While preformed antibody responses dominate Gal antigens, it has been shown that elicited Abs responses can occur in cardiac XTx also towards these other antigens (i.e., non-Gal antigens). Cellular Xenograft . . .

     

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