HIGHLIGHTS
- who: Ceylan Verda Bitirim from the Stem Cell InstituteAnkara University have published the research: Cardioprotective effect of extracellular vesicles derived from ticagrelor-pretreated cardiomyocyte on hyperglycemic cardiomyocytes through alleviation of oxidative and endoplasmic reticulum stress, in the Journal: Scientific Reports Scientific Reports
- what: The authors demonstrated an important effect of ticagrelor, a drug directly targeting u00adP2Y12-receptors, on cardiomyocytes-derived EVs in hyperglycemic cardiomyocytes. The major limitation of the study is that no in_vivo data were presented to show the therapeutic effect of ticagrelor via regulating paracrine signaling of cardiomyocytes in the diabetic rat. The . . .
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