Cardiovirus leader proteins retarget rsk kinases toward alternative substrates to perturb nucleocytoplasmic traffic

HIGHLIGHTS

• who: Belu00e9n Lizcano-Perret et al. from the Editor: George ABelov, University of Maryland have published the paper: Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic, in the Journal: (JOURNAL) of June/23,/2022
• what: Using an analog-sensitive mutant kinase the authors show that in infected cells L can trigger to use NUP98 and NUP214 as direct substrates. The authors show that a short protein encoded by small RNA viruses of the genus can act as an adapter molecule which recruits and directs activated kinases toward the NPCs where . . .
  

   

  

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