HIGHLIGHTS
- who: KO R S M et al. from the DepartmentUniversity of Michigan, Ann Arbor, Michigan, USA have published the article: Cargo selection in endoplasmic_reticulum-to-Golgi transport and relevant diseases, in the Journal: (JOURNAL)
SUMMARY
Early immunoelectron microscopy and in_vitro COPII reconstitution studies demonstrated that some secretory cargoes are selectively concentrated into COPII vesicles/tubules. The human SAR1A and SAR1B paralogs differ at only 20 of 198 amino_acid residues. Though the average degree of amino_acid sequence identity for orthologous proteins between the human and mouse genomes is about 85%, each of the human . . .

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