Carriers of loss-of-function mutations in ext display impaired pancreatic beta-cell reserve due to smaller pancreas volume

HIGHLIGHTS

• who: Sophie J. Bernelot Moens et al. from the of Paediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands, have published the Article: Carriers of Loss-of-Function Mutations in EXT Display Impaired Pancreatic Beta-Cell Reserve Due to Smaller Pancreas Volume, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0115662]. December 26, 2014 of /1371/
• what: The authors designed a dedicated series of investigations to unravel the effect of disrupted heparan sulfate synthesis on beta-cell function and mass, as well as insulin secretion, in humans with heterozygous loss of . . .
  

   

  

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