HIGHLIGHTS
- who: Zengxin Jiang from the (UNIVERSITY) have published the Article: Cartilage targeting therapy with reactive oxygen species-responsive nanocarrier for osteoarthritis, in the Journal: (JOURNAL)
- what: This study provided a delivery system through ROS-responsive regulation of the therapeutic agents into chondrocytes of the cartilage and confirmed the exact biological mechanisms of this innovative strategy.
- how: In vitro biomolecular results showed that compared with OL alone MSN-OL could significantly activate Nrf2/HO-1 signaling pathway which exhibited better ROS-scavenging proficiency and greater anti-apoptotic ability to protect mitochondrial membrane potential of . . .
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