Case-control investigation of invasive salmonella disease in malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission

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SUMMARY

    Although they might be transmitted in a zoonotic fashion (analogous with diarrhoeal disease in HICs), previous household or food-chain studies have failed to find any evidence to link the NTS strains responsible for invasive disease with either domestic animals or with food production, while disease case-control studies have established genomic links between isolates from cases and from their healthy household family-members. To address the knowledge gap concerning the reservoirs and transmission of NTS Salmonella strains responsible for invasive Salmonella infections, the authors conducted a cross-sectional case-control study following iNTS . . .

     

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