Case report: exceptional response to poziotinib in patient with metastatic non-small cell lung cancer with egfr exon 20 insertion mutation

HIGHLIGHTS

• who: Arsela Prelaj from the University of Kansas Medical Center, United States have published the article: Case Report: Exceptional Response to Poziotinib in Patient with Metastatic Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutation, in the Journal: (JOURNAL)
• what: EGFRex20ins mutations continue to represent an urgent unmet clinical need, especially in the front line setting.

SUMMARY

EGFR gene activating mutations are detected in approximately 10%-15% of Caucasian patients with metastatic non-small-cell lung cancer (mNSCLC). Amongst the uncommon EGFR mutations, exon 20 insertions (EGFRex20ins) and duplications . . .

 



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