HIGHLIGHTS
- who: Shu-Na Chen from the Tianjin Medical University, China have published the research: Case report: ISL2 is involved in malignant transformation in a patient with multiple relapsed oligodendroglioma, in the Journal: (JOURNAL)
- what: To further verify the important role of ISL2-mediated angiogenesis in the malignant transformation of oligodendrogliomas, the authors report a patient with recurrent oligodendroglioma whose glioma progressed from WHO grade II to grade III. The authors reported that the expression levels of ISL2 and angiogenesis-related genes increased with the malignant transformation of oligodendroglioma.
- how: Specifically the authors evaluated . . .
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