Case report: olaparib shows satisfactory clinical outcomes against small cell esophageal carcinoma with atm mutation

HIGHLIGHTS

  • who: Weiwei Wang from the Jinan University, China have published the research: Case Report: Olaparib Shows Satisfactory Clinical Outcomes Against Small Cell Esophageal Carcinoma With ATM Mutation, in the Journal: (JOURNAL)
  • what: The authors report identification of one driver mutation in the ATM gene, using a case of SCEC based on analysis of next generation sequencing data derived from an esophagus lesion and ctDNA (circulating tumor DNA). The authors show successful treatment of this condition using olaparib, with satisfactory clinical outcomes. In the present study, a ATM mutation were identified in a 56 years-old . . .

     

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