Case report pd-1 checkpoint blockade in patients for acute myeloid leukemia after hsct relapse resulted in severe gvhd and shlh

HIGHLIGHTS

• who: Zhi zhuo Du et al. from the Children`s Hospital of Suzhou University, Suzhou, China have published the research: Case Report PD-1 Checkpoint Blockade in Patients for Acute Myeloid Leukemia after HSCT Relapse Resulted in Severe GVHD and sHLH, in the Journal: Case Reports in Hematology of 22/Dec/2022
• what: The authors report two AML patients who relapsed after HSCT treated with carrizumab, who developed sHLH and severe aGVHD, and were successfully treated with pulse therapy using high-dose MP and other immunosuppressants.

SUMMARY

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