Case report: whole-genome sequencing of serially collected haemophilus influenzae from a patient with common variable immunodeficiency reveals within-host evolution of resistance to trimethoprim-sulfamethoxazole and azithromycin after prolonged treatment

HIGHLIGHTS

  • who: Paul Christoffer Lindemann from the University of London, United Kingdom have published the Article: Case Report: Whole-Genome Sequencing of Serially Collected Haemophilus influenzae From a Patient With Common Variable Immunodeficiency Reveals Within-Host Evolution of Resistance to Trimethoprim-Sulfamethoxazole and Azithromycin After Prolonged Treatment, in the Journal: (JOURNAL)
  • what: We describe chromosomal mutations responsible for within-host evolution of resistance to trimethoprim-sulfamethoxazole and azithromycin in a persisting NTHi strain in the respiratory tract of a CVID patient, after prolonged exposure to these antibiotics.

SUMMARY

    Recurrent infections and prolonged . . .

     

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