Caspase-11 contributes to site-1 protease cleavage and srebp1 activation in the inflammatory response of macrophages

HIGHLIGHTS

  • who: Yinglan Cheng and collaborators from the KIIT University, India have published the paper: Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages, in the Journal: (JOURNAL)
  • what: The authors assessed the role of the caspase-11/S1P/ SREBP1 axis in the acute inflammatory response to LPS.
  • how: The results indicated that caspase-11 directly associates with S1P. For experiments involving two factors data were analyzed using two-way ANOVA followed by Tukey`s tests except where otherwise indicated.
  • future: The functional role . . .

     

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