HIGHLIGHTS
- who: Anwari Akhter et al. from the Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Center for Microbial Interface Biology and the Department of Internal Medicine, Ohio State UniversityEditor: Dana JPhilpott, University of Toronto, Canada have published the research work: Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection, in the Journal: (JOURNAL)
- what: Using the intracellular pathogen L pneumophila the authors show that upon infection of murine macrophages caspase-7 was activated downstream of the Nlrc4 inflammasome and required caspase-1 activation. The authors demonstrate that caspase-7, but not . . .
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