Caspase-dependent proteolysis of human ribonucleotide reductase small subunits r2 and p53r2 during apoptosis*

HIGHLIGHTS

  • who: Ali Tebbi from the (UNIVERSITY) have published the article: Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis*, in the Journal: (JOURNAL) of May/29,/2015
  • what: The authors could not detect any degradation product of protein R2 in the experiments described in Fig 8 using one antibody recognizing the N-terminal part of the protein (I-15). This work reports for the first time the existence of a caspase-mediated proteolytic regulation of p53R2, releasing the C-terminal extremity involved in R1 recognition.
  • how: This result . . .

     

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